ニュース

The Critical Challenge: Maintaining Particle Size During Scale-Up The transition of Lipid Nanoparticles (LNPs) from a controlled laboratory environment to clinical-grade production is one of the most significant hurdles in modern drug delivery. While the industry has seen a surge in nucleic acid therapeutics, many promising candidates stall during the scale-up phase. The core challenge […]

In the modern oncology and rare disease landscape, the most promising therapeutic candidates—such as mRNA, siRNA, and high-potency APIs (HPAPIs)—often suffer from poor aqueous solubility or rapid systemic degradation. Lipid Nanoparticles (LNPs) have emerged as the gold standard for delivering these “hard-to-make” drugs, yet many programs stall during the transition from laboratory bench to clinical production. The […]