Whitepapers

Innovations in API Manufacturing of Small Molecule Drugs

June 12, 2025

How can the pharmaceutical industry improve efficiency, sustainability, and adaptability in API manufacturing?

In this whitepaper, Dirk-Jan van Zoelen, PhD, explores how applying the 6M framework—Manpower, Method, Machine, Material, Measurement, and Mother Nature—enables scientific and operational innovation across the development and scale-up of small molecule APIs.

Learn how emerging technologies like AI, flow chemistry, enzymatic catalysis, and greener synthesis approaches are helping reduce costs and environmental impact—while ensuring quality and regulatory robustness.

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