Nanoparticle manufacturing has typically relied on batch technology, but as batch sizes increase, scale-up issues become a concern. Flow technology offers a solution to these issues, operating a manufacturing process under constant process parameters to produce nanoparticle products of consistent quality, irrespective of batch size.
But while flow technology offers advantages in scale-up issues and process safety, it is not always the better choice for every process. Every nanoparticle production process is unique, and the decision to use batch or flow technology needs to be evaluated on a case-by-case basis.
Our experts Silvie Meeuwissen, Director Process R&D and Manufacturing Nanomedicines, and Wouter Veldmate, MSc. Senior Scientist – Process Development Nanomedicines provide key insights about flow technology in this Q&A with Ardena Experts.
