DVS involves exposing solid samples to varying humidity conditions while closely monitoring weight changes, offering valuable insights into water-material interactions. María Jesús Martín, Project Leader in Solid State Research. highlights DVS’s crucial role in stability studies, investigating polymorphism and hydrate formation, quality control, and optimizing drying processes in pharmaceutical development.

This document also explores the equipment used for DVS, its application in studying different solid forms, and a classification system for hygroscopicity. Discover the ins and outs of DVS, including its limitations, illustrated with practical examples of sorption/desorption profiles.

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